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The mean estimated ALSFRS-R total score was 42.8 at baseline, 30.6 at month 12 and 18.4 at month 24 in treated subjects, with a mean slope of 1.0, as compared to 41.9, 25.4 and 8.8 in not treated subjects, with a mean slope of 1.4 (slope difference: 0.4

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Wilhite K, Reid JM, Lane M